Early warning scores to detect deterioration and sepsis risk, and how to act on each score band.
At the bedside
- 1
Score every set of observations
Calculate NEWS2 at every observation round. Use SpO2 Scale 2 (target 88-92%) only for patients with documented hypercapnic respiratory failure, prescribed by a doctor.
- 2
Score 0
Routine monitoring at least every 12 h.
- 3
Score 1-4
Nurse informs the registered nurse in charge, who decides on escalation; observations at least every 4-6 h.
- 4
Score 3 in any single parameter
Low-medium risk: urgent ward-based review by a doctor; observations at least hourly.
- 5
Score 5-6 (key threshold)
< 30 minMedium risk: urgent review within 30 minutes by a clinician competent in acute illness; consider sepsis, start the sepsis screen; observations at least hourly.
- 6
Score ≥ 7
ImmediateHigh risk: emergency assessment by a critical care-competent team (rapid response/ICU outreach), continuous monitoring, consider transfer to HDU/ICU.
- 7
Apply qSOFA in suspected infection
qSOFA ≥ 2 flags higher risk of death or prolonged ICU stay. Do not use it as the only screening tool for sepsis; a negative qSOFA does not exclude sepsis. Measure SOFA and lactate.
NEWS2 scoring (summary)
| Parameter | 3 | 2 | 1 | 0 | 1 | 2 | 3 |
|---|---|---|---|---|---|---|---|
| Resp rate (/min) | ≤ 8 | - | 9-11 | 12-20 | - | 21-24 | ≥ 25 |
| SpO2 Scale 1 (%) | ≤ 91 | 92-93 | 94-95 | ≥ 96 | - | - | - |
| SpO2 Scale 2 (%) | ≤ 83 | 84-85 | 86-87 | 88-92 or ≥ 93 on air | 93-94 on O2 | 95-96 on O2 | ≥ 97 on O2 |
| Air or oxygen | - | Oxygen | - | Air | - | - | - |
| Systolic BP (mmHg) | ≤ 90 | 91-100 | 101-110 | 111-219 | - | - | ≥ 220 |
| Pulse (/min) | ≤ 40 | - | 41-50 | 51-90 | 91-110 | 111-130 | ≥ 131 |
| Consciousness | - | - | - | Alert | - | - | New confusion, V, P or U |
| Temperature (C) | ≤ 35.0 | - | 35.1-36.0 | 36.1-38.0 | 38.1-39.0 | ≥ 39.1 | - |
Columns: points scored for low values (left), 0 = normal, points for high values (right).
NEWS2 clinical response
| Score | Risk | Monitoring | Response |
|---|---|---|---|
| 0 | Low | 12-hourly | Routine |
| 1-4 | Low | 4-6 hourly | Nurse in charge assesses |
| 3 in one parameter | Low-medium | Hourly | Urgent ward doctor review |
| 5-6 | Medium | Hourly | Urgent review < 30 min, consider sepsis |
| ≥ 7 | High | Continuous | Emergency critical care team review |
Calculators for this topic
References
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NEWS2 escalation pathway
Step 1 of ~4
Calculate NEWS2 (correct SpO2 scale)
Based on Royal College of Physicians. Educational use; follow local protocol.
Pathophysiology
Early warning scores aggregate small deviations in several vital signs because each alone is insensitive. NEWS2 (2017) added a separate SpO2 scale for hypercapnic patients and 'new confusion' to the consciousness parameter, reflecting delirium as an early sign of sepsis.
Evidence
- NEWS discriminated patients at risk of cardiac arrest, unanticipated ICU admission or death within 24 h better than 33 other early warning scores (AUROC 0.89 for death) [Smith 2013].
- qSOFA was derived as a bedside prompt in Sepsis-3; it predicts mortality but has poor sensitivity for sepsis [Sepsis-3 2016].
- SSC 2026 recommends NEWS, NEWS2, MEWS or SIRS over qSOFA as a single screening tool (strong, moderate certainty); in 221,429 prehospital records NEWS2 performed best and qSOFA had the lowest sensitivity (23%) [SSC 2026]. SSC 2026 also suggests a 'code sepsis' or sepsis-huddle response after a positive screen (conditional).
Controversies
- NEWS2 Scale 2 is often misapplied, leading to under-scoring of hypoxaemia.
- Automated scoring in electronic records improves compliance but alarm fatigue is a real risk.
🇮🇳 India notes
- Paper-based NEWS2 charts work well in Indian wards; laminated pocket cards help nurses.
- In high nurse-to-patient ratios, prioritise RR, SpO2, SBP and sensorium at least 4-hourly in all newly admitted febrile patients during monsoon season.
References
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Test yourself
Module quiz · score 70% to complete the module
Educational reference for trained clinicians. Check doses against your hospital protocol and the patient in front of you.

