Structured head-to-toe assessment that treats life threats as they are found, before a diagnosis is made.
At the bedside
Timed steps- 1
Safety, response and help
0 minApproach safely, ask 'Are you all right?'. If no response and not breathing normally, start CPR and call the code team (go to Cardiac arrest module). If responsive but sick, call for senior help early and attach monitoring (SpO2, ECG, NIBP).
- 2
A - Airway
0-1 minLook, listen, feel: talking = patent. Signs of obstruction: stridor, gurgling, see-saw breathing, silence with effort. Head tilt-chin lift / jaw thrust, suction, oro- or nasopharyngeal airway; give high-flow O2 15 L/min via non-rebreather. Anaphylaxis or burns: early anaesthetic help.
- 3
B - Breathing
1-3 minCount RR (normal 12-20), SpO2, work of breathing, chest expansion, trachea, percussion, auscultation. Treat: target SpO2 94-98% (88-92% if hypercapnic risk), nebulise bronchospasm, decompress tension pneumothorax, sit up. Send ABG.
- 4
C - Circulation
3-6 minHR, BP, CRT (> 2 s abnormal), skin colour and temperature, JVP, urine output. Two large-bore cannulae (16-18G), send bloods incl. lactate, cultures, cross-match. Hypotension: 250-500 mL crystalloid bolus and reassess; look for bleeding, sepsis, cardiac cause. 12-lead ECG.
- 5
D - Disability
6-8 minAVPU or GCS, pupils, capillary glucose (treat < 70 mg/dL), lateralising signs, seizures, drugs (opioids, sedatives). Protect the airway if GCS ≤ 8 or falling, unless rapidly reversible (e.g. hypoglycaemia, opioid).
- 6
E - Exposure
8-10 minFully expose with dignity: temperature, rashes (meningococcal, dengue petechiae), wounds, drains, bleeding, calf swelling, pressure areas, bite marks (snakebite). Check charts, drug chart and fluid balance.
- 7
Reassess, escalate, document
10-15 minRepeat ABCDE after every intervention. Communicate with ISBAR to the senior/ICU, decide ceiling of care and destination (ward with closer monitoring, HDU, ICU). Write a timed note with NEWS2 and plan.
First treatment in A/B
Oxygen
- Dose
- 15 L/min non-rebreather if critically ill; then titrate to SpO2 94-98% (88-92% if hypercapnic risk)
- Target
- SpO2 94-98% or 88-92%
Fluid challenge in C
Balanced crystalloid (Ringer lactate / Plasma-Lyte)
- Dose
- 250-500 mL over 10-15 min, reassess
- Worked example
- 70 kg with SBP 82 and cold peripheries: 500 mL RL over 15 min, recheck BP, HR, CRT, chest
Stop at signs of fluid intolerance; think early vasopressor if MAP < 65 mmHg persists.
Hypoglycaemia in D
Dextrose 25% (or 50%)
- Dose
- 25 g (100 mL 25% dextrose)
- Target
- Glucose > 70 mg/dL, recheck at 15 min
ABCDE quick reference
| Step | Look for | Immediate actions |
|---|---|---|
| A | Stridor, gurgling, snoring, paradoxical movement, silence | Airway manoeuvres, suction, OPA/NPA, O2 15 L/min, call anaesthesia |
| B | RR < 8 or > 25, SpO2 < 92%, accessory muscles, unequal air entry | Titrated O2, nebulisers, sit up, needle decompression, ABG, CXR/ultrasound |
| C | HR > 130 or < 40, SBP < 90, CRT > 2 s, mottling, oliguria | IV access x2, bloods + lactate, fluid bolus, ECG, stop bleeding |
| D | GCS fall ≥ 2, glucose < 70 mg/dL, unequal pupils, seizure | Glucose, naloxone if opioid, benzodiazepine for seizure, protect airway |
| E | Fever/hypothermia, rash, bleeding, wounds, bites | Cultures, antibiotics if sepsis, warming/cooling, source search |
Calculators for this topic
ABCDE assessment loop
Step 1 of ~3
Decision: Responsive and breathing normally?
Based on Resuscitation Council UK. Educational use; follow local protocol.
Pathophysiology
Most in-hospital cardiac arrests are preceded by hours of abnormal vital signs (rising respiratory rate, falling SpO2, tachycardia, hypotension, confusion). The ABCDE sequence follows the order in which problems kill: airway obstruction kills in minutes, hypoxaemia within minutes, shock within minutes to hours, and neurological or exposure problems usually more slowly.
Evidence
- The ABCDE approach is consensus-based (Resuscitation Council UK, ERC, ATLS) and is recommended for all acutely ill patients regardless of diagnosis [Thim 2012].
- Respiratory rate is the single most sensitive early marker of deterioration and the most frequently omitted vital sign.
- Delayed ED-to-ICU transfer (> 6 h) was associated with higher mortality in a US cohort, supporting early escalation [Chalfin 2007].
Controversies
- How much structured assessment versus a parallel team approach: in a full team, A to E is assessed simultaneously by different members; the junior alone should still go in order.
- Fluid bolus size is moving down (250-500 mL with reassessment) rather than fixed 30 mL/kg for every hypotensive patient; see the Shock module.
🇮🇳 India notes
- In Indian wards one doctor may cover 60-100 patients at night; train nurses to trigger escalation on NEWS2 or 'worried' without waiting for the doctor's round.
- Always consider India-specific causes during E: snake or scorpion bites, OP poisoning smell, dengue petechiae, eschar of scrub typhus (axilla, groin, under breasts).
- Check oxygen supply (cylinder vs pipeline) when transferring; see the oxygen cylinder calculator.
References
Test yourself
Module quiz · score 70% to complete the module
Educational reference for trained clinicians. Check doses against your hospital protocol and the patient in front of you.

