Haemodynamic monitoring

Cardiac output monitoring

Reviewed Nov 2026·1 references
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Choosing between echo, pulse contour, transpulmonary thermodilution and pulmonary artery catheter, and what each number means.

Definition
Cardiac output (CO) = HR x stroke volume; cardiac index = CO/BSA (normal 2.5-4.0 L/min/m²). Advanced monitoring is indicated in shock not responding to initial therapy, complex mixed shock, or RV failure/ARDS where fluid balance is critical.

At the bedside

  1. 1

    Start with echo

    ESICM 2014 recommends echocardiography as the first-line tool to assess type of shock. LVOT VTI x LVOT area x HR estimates CO; normal VTI 18-22 cm.

  2. 2

    Choose advanced monitoring if not responding

    Transpulmonary thermodilution (e.g. PiCCO, EV1000/VolumeView) or pulmonary artery catheter in severe shock, especially with ARDS or RV dysfunction.

  3. 3

    Pulse contour analysis

    Uncalibrated (FloTrac, LiDCO rapid, ProAQT) or calibrated (PiCCO). Good for trends and SVV; inaccurate with arrhythmia, aortic regurgitation, IABP, rapid vasopressor changes and damped traces.

  4. 4

    Transpulmonary thermodilution

    Cold saline (15-20 mL) via CVC, femoral arterial thermistor: CO, GEDVI (preload, normal 680-800 mL/m²), EVLWI (lung water, > 10 mL/kg = pulmonary oedema), PVPI (> 3 = permeability oedema).

  5. 5

    Pulmonary artery catheter

    CO (thermodilution), PAOP (wedge, LV filling), PAP, SvO2, PVR. Use in complex RV failure, pulmonary hypertension, cardiogenic shock and cardiac surgery; no routine benefit in general ICU patients.

  6. 6

    Integrate, don't chase numbers

    Use CO with MAP, perfusion markers (lactate, CRT, ScvO2, CO2 gap) and organ function to choose fluid vs vasopressor vs inotrope.

Cardiac output tools compared

ToolInvasivenessKey outputsLimitations
EchocardiographyNoneLV/RV function, VTI, CO, pericardium, valvesOperator dependent, intermittent
Uncalibrated pulse contourArterial lineCO trend, SVVArrhythmia, AR, vasoplegia, damping
Transpulmonary thermodilutionCVC + femoral arterial lineCO, GEDVI, EVLWI, PVPI, SVVRecalibrate every 8 h / after changes; cost
Pulmonary artery catheterPA catheterCO, PAOP, PAP, SvO2, PVRComplications (arrhythmia, PA rupture), interpretation errors
Bioreactance / oesophageal DopplerNon-/minimally invasiveCO trendValidation varies
Red flag · call your senior now
Cardiac index < 2.2 L/min/m² with hypoperfusion = low-output shock: inotrope/mechanical support evaluation.
Pitfall
Trusting uncalibrated pulse-contour CO in severe vasoplegia, AF or after large vasopressor changes.
Pitfall
Measuring PAOP at peak inspiration instead of end-expiration.
Pearl
EVLWI from thermodilution helps stop fluids in ARDS: values > 15 mL/kg mean severe pulmonary oedema.

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