The IVC estimates right atrial pressure in spontaneously breathing patients but predicts fluid responsiveness poorly, especially on the ventilator. A plethoric IVC with abnormal hepatic, portal and intrarenal Doppler (VExUS grade 2-3) signals venous congestion: stop fluids and consider decongestion.
At the bedside
Timed steps- 1
IVC
MeasureSubcostal long axis, 1-2 cm from RA junction. Spontaneous breathing: < 2.1 cm collapsing > 50% suggests low RAP (~3 mmHg); > 2.1 cm collapsing < 50% suggests high RAP (~15 mmHg).
- 2
Ventilated
CautionIVC distensibility > 18% may suggest fluid responsiveness in fully ventilated, passive patients with Vt ≥ 8 mL/kg; otherwise unreliable.
- 3
VExUS
If plethoricIVC ≥ 2 cm, then hepatic vein (S < D or reversed S), portal vein pulsatility (≥ 30% mild, ≥ 50% severe), intrarenal venous Doppler (biphasic or monophasic).
- 4
VExUS
Grade0: IVC < 2 cm. 1: plethoric, normal/mild patterns. 2: one severe pattern. 3: ≥ 2 severe patterns. Grade 3 associated with AKI after cardiac surgery.
- 5
Congestion
ActStop fluids; diuretics or ultrafiltration if perfusion allows; treat RV failure.
References
- 1
- 2
IVC and congestion
Step 1 of ~3
Decision: IVC ≥ 2 cm?
Based on Beaubien-Souligny W, Rola P, Haycock K, et al. Educational use; follow local protocol.
Evidence
- FoCUS 2014: IVC size and collapsibility estimate RAP in spontaneously breathing patients.
- VExUS 2020: combined Doppler grading predicted AKI after cardiac surgery better than CVP.
Controversies
- VExUS has limited validation outside cardiac surgery and in arrhythmias such as AF.
🇮🇳 India notes
- Doppler-capable ultrasound is needed for VExUS; many Indian ICU machines have it but training is variable.
References
- 1
- 2
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