Treat a regular wide-complex tachycardia as VT until proven otherwise. Unstable: synchronised cardioversion. Stable: cardioversion under sedation or IV amiodarone. Torsades: magnesium and remove QT drugs. Electrical storm: sedate, beta-block, amiodarone, correct electrolytes, treat ischaemia.
At the bedside
Timed steps- 1
Pulse?
0 minPulseless: ALS shockable pathway (module 2). Pulse present: assess stability.
- 2
Synchronised cardioversion
Unstable120-200 J biphasic, escalate; sedate if conscious. Polymorphic VT: unsynchronised shock.
- 3
Cardioversion or drug
Stable monomorphicESC 2022 favours synchronised cardioversion if anaesthesia risk is low; otherwise amiodarone 300 mg IV over 10-60 min (procainamide where available). Adenosine only for regular monomorphic WCT when SVT with aberrancy is likely.
- 4
QT-related
TorsadesMagnesium 2 g IV; stop QT-prolonging drugs; K+ to 4.5-5; if bradycardia-dependent, isoprenaline or overdrive pacing.
- 5
≥ 3 sustained VT/VF in 24 h
Electrical stormDeep sedation (± intubation), beta-blockade (propranolol or esmolol), amiodarone, correct K+/Mg2+, urgent angiography if ischaemia; ICD reprogramming; ablation or MCS in refractory cases.
- 6
Find the cause
AfterIschaemia, scar, cardiomyopathy, myocarditis, electrolytes, drugs (QT), channelopathy. Cardiology referral for ICD/ablation.
Stable VT / storm
Amiodarone
- Dose
- 300 mg over 10-60 min, then 900 mg/24 h
Torsades de pointes
Magnesium sulfate
- Dose
- 2 g over 10-15 min; repeat or infuse 3-10 mg/min if recurs
Clues that a wide-complex tachycardia is VT
| Feature | Suggests VT |
|---|---|
| History | Previous MI, cardiomyopathy, structural heart disease |
| AV dissociation | P waves marching through, capture or fusion beats |
| QRS width | > 160 ms (LBBB-like) or > 140 ms (RBBB-like) |
| Concordance | All precordial complexes positive or all negative |
| Axis | Extreme (northwest) axis |
Calculators for this topic
References
- 1
- 2
Regular wide-complex tachycardia with pulse
Step 1 of ~3
Decision: Unstable?
Based on Zeppenfeld K, Tfelt-Hansen J, de Riva M, et al; Part 9: Adult Advanced Life Support: 2025 American Heart Association Guidelines for CPR and ECC. Educational use; follow local protocol.
Evidence
- ESC VA 2022: synchronised cardioversion first line for tolerated sustained monomorphic VT when anaesthetic risk is low; procainamide or amiodarone otherwise; management of electrical storm and torsades.
- AHA 2025: unsynchronised shocks for polymorphic VT; avoid calcium-channel blockers in WCT.
🇮🇳 India notes
- Procainamide is not available in India; amiodarone and lidocaine are the IV options.
- Organophosphate and aluminium phosphide poisoning cause QT prolongation and ventricular arrhythmias (module 28).
References
- 1
- 2
Test yourself
Module quiz · score 70% to complete the module
Previous
AF with rapid ventricular response in the ICU
Next
Bradycardia, heart block and temporary pacing
Educational reference for trained clinicians. Check doses against your hospital protocol and the patient in front of you.

