Most sting deaths are from anaphylaxis, treated with IM adrenaline. Massive envenomation from multiple stings causes delayed toxicity – rhabdomyolysis, haemolysis, AKI, myocardial injury – even without allergy; monitor for 24 h.
At the bedside
Timed steps- 1
Immediately
AnaphylaxisAdrenaline 0.5 mg IM (0.01 mg/kg child), repeat every 5-15 min; lie flat, oxygen, IV fluid boluses.
- 2
Promptly
Remove stingsScrape or pluck; speed matters more than method.
- 3
Risk stratify
Multiple stingsDozens to hundreds of stings: check CK, haemoglobin, LDH, bilirubin, creatinine, troponin, urine myoglobin; monitor 24 h.
- 4
Organ care
SupportiveHydrate for rhabdomyolysis, RRT for AKI, treat hyperkalaemia; delayed ARDS and myocarditis possible.
- 5
Allergy
DischargeRefer for allergy evaluation and venom immunotherapy; teach adrenaline autoinjector use where available.
Hymenoptera sting
Step 1 of ~4
Decision: Anaphylaxis?
Based on Cardona V, Ansotegui IJ, Ebisawa M, et al. Educational use; follow local protocol.
Evidence
- WAO 2020: adrenaline IM is first-line; antihistamines and glucocorticoids are adjuncts only.
🇮🇳 India notes
- Mass attacks by rock bees (Apis dorsata) and hornets occur in forested and hill regions (Western Ghats, North-East).
References
Test yourself
Module quiz · score 70% to complete the module
Educational reference for trained clinicians. Check doses against your hospital protocol and the patient in front of you.

