ICU care bundles and infection prevention

Hand hygiene, standard and transmission-based precautions

Reviewed Nov 2026·3 references
New· views rounded down, updated weekly

WHO 5 moments, choosing contact, droplet or airborne precautions, and MDRO cohorting.

Definition
Hand hygiene is the single most important measure to prevent healthcare-associated infection. Standard precautions apply to every patient; transmission-based precautions (contact, droplet, airborne) are added for specific organisms.

At the bedside

  1. 1

    WHO 5 moments

    Before touching a patient; before a clean/aseptic procedure; after body fluid exposure risk; after touching a patient; after touching patient surroundings.

  2. 2

    Method

    Alcohol-based hand rub 20-30 s for most situations; soap and water 40-60 s when hands are visibly soiled and for C. difficile or norovirus.

  3. 3

    Standard precautions

    Hand hygiene, PPE for anticipated exposure, respiratory hygiene, safe sharps, cleaning of equipment and environment, safe waste and linen handling.

  4. 4

    Contact

    Gloves and gown on entry; dedicated equipment; single room or cohort: MDR Gram-negatives (CRE, CRAB), MRSA, VRE, C. difficile, scabies.

  5. 5

    Droplet

    Surgical mask within 1-2 m; single room or cohort: influenza, meningococcal disease (first 24 h of effective therapy), pertussis, diphtheria.

  6. 6

    Airborne

    N95 respirator (fit-tested), airborne infection isolation room (negative pressure, ≥ 12 air changes/h where available): pulmonary/laryngeal TB, measles, varicella and disseminated zoster.

  7. 7

    Aerosol-generating procedures

    Intubation, NIV, bronchoscopy, open suctioning in patients with respiratory pathogens: N95, eye protection, gown and gloves.

  8. 8

    Audit and feedback

    Direct observation audits (WHO tool), surveillance of HAIs and MDROs, feedback to staff.

Transmission-based precautions

TypeExamplesPPE and placement
ContactCRE, CRAB, MRSA, VRE, C. difficile, scabiesGown + gloves; single room or cohort; dedicated equipment
DropletInfluenza, meningococcus, pertussis, diphtheriaSurgical mask; single room or cohort; ≥ 1 m spacing
AirbornePulmonary TB, measles, varicella, disseminated zosterN95; negative-pressure room; door closed
Contact + airborneVaricella, disseminated zosterGown, gloves and N95
Red flag · call your senior now
Cluster of the same MDR organism in 2 or more patients: notify the infection control team for outbreak investigation.
Pitfall
Gloves used as a substitute for hand hygiene, or the same gloves worn between patients.
Pitfall
Alcohol rub for C. difficile - it does not kill spores; wash with soap and water.
Pearl
Most hand hygiene failures occur at moments 4 and 5 (after patient or surroundings contact) - put alcohol rub at every bed space.

Test yourself

Module quiz · score 70% to complete the module

Educational reference for trained clinicians. Check doses against your hospital protocol and the patient in front of you.