Before every ICU intubation, score anatomical difficulty (MACOCHA), identify physiological risks (hypoxaemia, hypotension, acidosis, RV failure), and run a checklist with a team brief and a stated Plan A-B-C-D.
At the bedside
Timed steps- 1
Is intubation needed now?
DecideFailure to protect airway, oxygenate or ventilate; anticipated course; procedural need. Call a senior early for predicted difficulty.
- 2
Anatomical risk: MACOCHA
ScoreMallampati III-IV (5), OSA (2), reduced cervical mobility (1), mouth opening < 3 cm (1), coma (1), severe hypoxaemia SpO2 < 80% (1), non-anaesthetist operator (1). Score ≥ 3 predicts difficult intubation.
- 3
Physiological risk
ScoreHypoxaemia, hypotension (SBP < 90, shock index > 0.9), severe metabolic acidosis, RV failure/pulmonary hypertension, raised ICP, full stomach.
- 4
Resuscitate before induction
OptimisePreoxygenate (next topic); start noradrenaline if hypotensive or shock index high; consider bicarbonate/ventilation plan in severe acidosis (match minute ventilation after intubation).
- 5
Equipment (STOP MAID / checklist)
PrepareSuction ×2, oxygen sources, BVM with PEEP valve, video and direct laryngoscopes, bougie, 2 tube sizes (7.0-8.0), second-generation SGA, scalpel-bougie-tube FONA kit, waveform capnography connected, drugs drawn and labelled.
- 6
Brief
TeamRoles (intubator, drugs, airway assistant with cricoid/BURP, monitor watcher, runner), verbalise Plan A (VL + bougie), Plan B (SGA), Plan C (face mask), Plan D (FONA) and the 'call out' SpO2.
- 7
Ramp and head up
PositionEar-to-sternal notch alignment; 20-30° head-up (reverse Trendelenburg if spine precautions) improves preoxygenation and reduces aspiration.
MACOCHA score
| Factor | Points |
|---|---|
| Mallampati III or IV | 5 |
| Obstructive sleep apnoea syndrome | 2 |
| Reduced mobility of cervical spine | 1 |
| Limited mouth opening < 3 cm | 1 |
| Coma | 1 |
| Severe hypoxaemia (SpO2 < 80%) | 1 |
| Non-anaesthesiologist operator | 1 |
| Total 0-12; ≥ 3 = predicted difficult |
Physiologically difficult airway: risk and response
| Risk | Before induction | During and after |
|---|---|---|
| Hypoxaemia | NIV or HFNC preoxygenation, PEEP, head up | Apnoeic oxygenation, bag-mask ventilation between induction and laryngoscopy |
| Hypotension / shock | Noradrenaline running, fluid if responsive, reduced-dose induction | Push-dose vasopressor ready; avoid big PEEP and high rates immediately |
| Severe metabolic acidosis | Avoid apnoea; consider bicarbonate or delay if possible | Set high minute ventilation matching pre-intubation breathing; ABG early |
| RV failure / pulmonary hypertension | Noradrenaline or vasopressin first, avoid hypoxia and hypercapnia | Low PEEP and Vt; inhaled vasodilator if available |
References
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Pre-intubation decision
Step 1 of ~5
Decision: Predicted anatomically difficult (MACOCHA ≥ 3, known difficult)?
Based on Higgs A, McGrath BA, Goddard C, et al; Tracheal intubation in critically ill adults with a physiologically difficult airway. Educational use; follow local protocol.
Evidence
- INTUBE (2021): 2964 intubations; ≥ 1 major adverse peri-intubation event in 45.2% (cardiovascular instability 42.6%, severe hypoxaemia 9.3%, cardiac arrest 3.1%).
- DAS critically ill 2018: checklist, team brief, video laryngoscope availability, capnography, and a stepwise failed-airway plan.
- ESICM 2024 Delphi: consensus statements for the physiologically difficult airway.
Controversies
- Awake intubation in the ICU is rarely possible in agitated, hypoxaemic patients.
🇮🇳 India notes
- The AIDAA 2016 ICU guideline was written for Indian practice and recommends checklists, video laryngoscopes where available and second-generation SGAs.
- Many Indian ICUs depend on residents for night intubations; MACOCHA awards a point to the non-anaesthetist operator: escalate early.
References
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