(AG − 12) ÷ (24 − HCO₃⁻). Detects a second metabolic process in a high-AG acidosis.
mmol/L
mmol/L
Delta ratio
1.40
Pure high-AG acidosis (1-2; DKA can be ≈ 1)
Hyperchloraemic normal-AG acidosis
Mixed high-AG and normal-AG acidosis
Pure high-AG acidosis (1-2; DKA can be ≈ 1)
High-AG acidosis plus metabolic alkalosis or chronic respiratory acidosis
Formula
(ag - 12) / (24 - hco3)
References
Used in
Calculators support, not replace, clinical judgement. Check inputs and units, and confirm doses with your unit protocol.